EXPERIMENTAL STUDY ON CASEIN PREVENTING IODINEDEFICIENT GOITRE IN RATS
- VernacularTitle:酪蛋白预防大鼠缺碘性甲状腺肿的实验研究
- Author:
An OUYANG
- Publication Type:Journal Article
- Keywords:
Casein Iodine-deficient goitre
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
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Abstract:
In this experimental study, Wistar rats were divided into 3 groups: Group A, 33 rats fed with diet purchased from endemic goitre area and iodine-free distilled water; Group B, 33 rats fed with the same diet of group A but 50% of casein was added and iodine-free distilled water; Group G, 33 rats fed with general rat's diet and ordinary tap water as control. After three and a half months, blood taken from ocular vein was measured for thyroid hormone and thyroid-stimulating hormone, and thyroid glands were taken for histologic examination.The results have proved that typical iodine deficient goitre and hypothyroid models have been successfully established in rats from group A and casein can prevent rats from iodine-deficient goitre and hypothyroidism. The mechanism might be that casein may enhance iodine transportation and utilization in thyroid.
