EFFECTS OF GATING MODIFIERS OF MEMBRANE IONIC CHANNEL ON EXCITABILITY OF NERVES
- VernacularTitle:膜离子通道闸门调制剂对神经兴奋性的影响
- Author:
Xiaomin WANG
;
Wanmei CHEN
- Publication Type:Journal Article
- Keywords:
Na channcl;
Gating current;
Gating modifiers;
Standard clectrical quantity
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Fffects of three gating modifiers of membrane ionic channel, aconitine (AC), deoxycholate (DOC) and Ca~(2+), on the excitability of nerves and the cxcitability index, standard clectrical quantity "a" were observed on 38 crayfish giant axons and 60 toad sciatic-peronael nerves. Results showed. that "a" is related to the activating rate of sodium channel and re(?)ts changes of clectrical quantity which is necded in opening the activation gating of sodium channel and producing the action potential.
