ESTROGEN AND PROGESTERONE RECEPTOR IN NONEPITHELIOGENIC OVARIAN TUMORS
- VernacularTitle:非上皮源性卵巢肿瘤性类固醇激素受体的研究
- Author:
Xuanmei LI
;
Xianying YAO
- Publication Type:Journal Article
- Keywords:
ovarian tumor, estrogen receptor, progesterone receptor
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Tissue samples from 42 patients with nonepitheliogenie ovarian tumors were assayed for estrogen receptor (ER) and progesterone receptor (PR) by Lce's fluorescent histochemical method. 2 of 4 theca cell tumor, 6 of 8 granulosa cell tumor had ER and PR. Among the 6 cases of granulosa cell tumor, 4 cases exhibited a high level of receptors (ER、PR positsve cell: 40%～50% of total tumor cells). As to teratomas, the epithelial cells of sweat glands, and cylindrical epithelia, as well as chondrocytes were ER PR positive. No ER-and PR-positive cells were found in endodermal sinus tumors, drsgerminomas and fibromas. Of 4 mataststic ovarian tumors, which were from gastrointestinal adenocarcinoma, tbe ER-and PR-positive cells were found in 1 specimen. The findings suggested that hormone-related therapy might be worthy of trying on thc patients with receptor positive granulosa cell tumor.
