DETECTION AND ANALYSIS OF HUMAN PAPILLOMAVIRUS DNA IN CONDYLOMA ACUMINATUM
- VernacularTitle:尖锐湿疣中人乳头瘤病毒DNA检测及存在情况初探
- Author:
Xiaoping DONG
;
Yukang YUAN
;
Yilan FANG
- Publication Type:Journal Article
- Keywords:
Condyloma acuminatum;
I luman papillomavirus;
Slot hybridization;
Southern blot
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Condyloma acuminatum is closely associated with human papillomavirus (HPV). In this study the method of slotting hybridization was used to detect the Specimens of 28 cases of condyloma acuminatum. Fourteen out of the 28 samples were positive for HPV 11 probe, the positive rate was 50% (14/28). Nine out of the 14 positive samples were digested with Bamll Ⅰ and Pst Ⅰ respectively to study the present state of DNA after using Southern blotting hybridization. It was shown that HPV 11 DNA were mainly present in a simple monometric episomal state in the condyloma acuminatum cells.
