EFFECT OF OQP ON CELL STRAIN OF HUMAN HEPATIC CARCINOMA SMMC-7721
- VernacularTitle:益气养血保元方中微量元素对肝癌细胞的影响
- Author:
Yingyun REN
;
Yuwu ZHANG
;
Ying XUE
- Publication Type:Journal Article
- Keywords:
OQp, cell siran of human hepatic carcinoma Ⅱ-TdR;
~(14)C-UR;
Trace element
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of OQP, a pormula of traditional Chinese medieine belonging to the category "Precription of the Reinforeing Qi and Enriching Blood for keep the Original Qi", on cell strain of human hepatic carcinoma SMMC-7721 was observed. The results showed that OQP depressed the incorporation of both ~3H-TdR and ~(14)C-UR in cells of hepatic carcinoma. This indicated that OQP inhibited the synthesis of DNA and RNA, and the growth of the cancer cell. Such effect may result from the low ratio Cu/Zn and the high content of Se in OQP. In conclusion, in this study it has been demonstrated that OQP can not only improve the general condition of patients in advanced liver cancer and lcukopenia of patients in chemotherapy and radiotherapy, but also can inhibite the growth of the cell of hepatic carcinoma directly.
