INITIAL STUDY ON MACHANISM OF INCREASING ?_2-m IN CSF OF PATIENTS WITH ACUTE CEREBROVASCULAR DISEASE
- VernacularTitle:急性脑血管病人脑脊液?_2—m升高机理的初步探讨
- Author:
Shengguang SHI
;
Tiancheng JIA
;
Wenchao LIU
- Publication Type:Journal Article
- Keywords:
ccrcbral hcmorrhage ccrcbral thrombosis;
ccrcbcal-spinal lluid;
?_2-microglobulin;
ccrcbrolvascular discasc
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The levels of ?_2-m、IgG and Alb in CSF of 13 patients with cerebral haemorrhage and 20 patients with cerebral thrombosis and the levels of ?_2-m in CSF of control group consisting of 14 eases were measured. It Was showed that the levels of ?_2-m in CSF of the two groups of the patients with cecrebrovascular disease were obviously higher than that of the control group and the levcls of ?_2-m in CSF of the two groups of the patients with cerebrovascular discase also had rclation to the levels of ?_2-m in serum of the groups of the patients themselves, the valucs of ?_2-m did not corre- lated with the valucs of IgG or Alb in CSF of the paticnts with cerebral hacmorrhage, but there existed a strong correlation between IgG and Alb in CSF of these patients. The values of ?_2-m, IgG and Alb in CSF of patients with cerebral thrombosis were exactly inversdy correlated with that of patients with cerebral haemorrhage. Reviewing some other data about ?_2-m the authors suggest that the clevated ?_2-m in CSf may indicate an increased cell-mediated immune phenomenon of central nervous system in teh pathological process of cerebral haemorrhage, but this phenomenon in the pathological process of cerebral thrombosis is not obviuos.
