ALTERATION OF Na-K-ATPase IN ERYTHROCYTE AND ITS INFLUENCING FACTORS IN DIABETIC PATIENTS
- VernacularTitle:糖尿病患者红细胞膜钠-钾-三磷酸腺苷酶活性改变及其影响因素
- Author:
Youhong WANG
- Publication Type:Journal Article
- Keywords:
Na-K-ATPase Diabetes mellitus Erythrocyte membrane
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
We measured the Na-K-ATPase activity in erythrocyte membrane from 21 diabetic patients and 21 normal subjects with molybdenum blue colorimetry for inorganic phosphorus and Lowry's method for protein. Changes of this enzyme in erythrocyte membrane before and after treatment were also observed ia 13 diabetics. Our results demonstrated that the Na-K-ATPase activities in erythrocyte membrane from diabetic patients were lower than that from normal controls and no significant difference in Na-K-ATPase activity was observed before and after treatment in diabetics. Experiments in vitro revealed that lowered Na-K-ATPase activity in erythrocyte membrane from diabetics was not related to the serum insulin and glucose levels.
