STUDY OF SERUM TRAb IN AUTOIMMUNE THYROID DISEASE WITH ABC- ELISA
- VernacularTitle:ABC—ELISA法检测自身免疫性甲状腺病患者TRAb的研究
- Author:
Lan HE
;
Hui GAO
- Publication Type:Journal Article
- Keywords:
Avidin-Biotin-Peroxidase Comples(ABC);
TSH recepor Antibody(TRAb);
Fischor rat thyroid line-5(FRTL-5);
Graves' Disease(GD);
Thyroid Stimulating Antibody(TSAb);
Thyroid Stimulating Blocking Antibody(TSBAb)
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
In this paper the investigation of using a new method-ABC-ELISA in assay of Autoimmune Thyroid Disease are presented. The sensitivity of ABC-ELISA is compared with that of standard ELISA; Its reliability is proven by the methods of detecting TSAb with FRTL-5. TRAb is detected by ABC-ELISA in 91% of untreated Graves'. TRAb is detected by Standard ELISA in 70% of untreated Graves'. The results of ABC-ELISA in 26 untreated Graves' are equal to that of the method of detecting TSAb with FRTL-5. Therefore, we consider that ABC-ELISA is a sensitive, reproducible, convenient method applicable to clinical practice.
