Study on the cell adhesion activity of CEA on tumor cell lines
- VernacularTitle:肿瘤细胞癌胚抗原的细胞粘附活性研究
- Author:
Baohua XUE
- Publication Type:Journal Article
- Keywords:
CEA;
Cell adhesion;
Adhesion molecules;
Cell aggregation
- From:
Chinese Journal of Immunology
1985;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
Cell adhesion activity of CEA on tumor cell lines was studied in the experiment.Single cell suspension of CEA positive ceils LoVo and HeLa aggregated respectively in RPMI1640 completemedium at 37℃ to form cell aggregates in different size.The cell aggregation could be specificly inhibited by anti-CEA polyclonal antibodies and purified CEA antigen.Similar results were obtained using cell adhesion assay.The experiment indicated that CEA is one of cell adhesion molecules.