PATTERNS OF GROWTH HORMONE SECRETION IN NORMAL ADULTS AND ACROMEGALIC PATIENTS
- VernacularTitle:正常成人及肢端肥大症患者的生长激素谱测定
- Author:
Yifan SHI
- Publication Type:Journal Article
- Keywords:
Pituitary GH-secreting tumor GH profile Circadian rhythm of GH secretion Acromegaly Stage of sleep
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
The secretory profile of GH was generated by 15-30 minutes sampling in 10 normal adults and 4 acromegalic patients. The 15-and 20-min sampling revealed more GH pulses than 30-min sampling, but the average amplitude of GH pulses and the amount of GH secreted were of the same. The normal females had more GH pulses in morning after waking and in the postabsorptive period after dinner., All .4 acromegalic patients had no big GH peak after the first deep wave sieep. In 2 acromegalic patients who had a 24-hour GH profile measurement, the male patient with normal blood sugar level had more GH pulses, but the female patient with diabetes mellitus had only a few GH pulses. Our results showed that the autonomous GH-secreting tumor remains under hypothalamic control to some extent.
