The immunoregulatory effect of TLSF_(JM) on the expression of T cell IL-2R and protein Tyrosine phosphorylation
- VernacularTitle:TLSF_(JM)对T细胞IL-2R表达和蛋白酪氨酸磷酸化的调节作用
- Author:
Haibin XIA
- Publication Type:Journal Article
- Keywords:
Inhibitory factor;
T Lymphocyte activation;
Protein Tyrosine phosphorylation;
Immunoregulation
- From:
Chinese Journal of Immunology
1985;0(06):-
- CountryChina
- Language:Chinese
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Abstract:
The immunoregulatory effect of TLSF_(JM) on the expression of T cell IL-2R and protein Tyrosine phosphorylation (PTP) was investigated by immunohistochemistry technique. The results showed that TLSF_(JM) can markedly suppress the expression of IL-2R and PTP on PHA or TPA-stimulated human PBMC and murine IL-2 dependent cell line CTLL-2. However, there was no effect of TLSF_(JM) on the production of IL-1、IL-2 and IL-6 that play an important role in the course of T Lymphocyte prolirferation and differentiation.
