Enterogenic infection and Multiple System Organ Failure in Bowel Ischemia and Reperfusion
- VernacularTitle:缺血后肠源性感染与多器官功能衰竭
- Author:
Zhiyong SHENG
- Publication Type:Journal Article
- Keywords:
Enterogenic infection Intestinal reperfusion injury Multiple system organ Failure
- From:
Chinese Journal of Trauma
1991;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
For the purpose of exploring the role of enterogenic infection in the pathogenesis of multiple system organ failure (MSOF), 40 dogs were subjected to partial occlusion of the superior mesenteric artery (SMA) for 1 hour. The results showed that ischemia and reperfusion of the intestine produced a breakdown of the intestinal mucosal barrier resulting in bacterial translocation. Subsequently, the liver, lung and cardiovascular system showed dysfunction of failure. Based on the experimental findings, it is suggested that the intestinal tract might be the target organ of reperfusion injury folowing hypovolemic shock, and it might pose as a "motor" of the development of MSOF.
