DETERMINATION OF SERUM ANTI-THYROTROPIN ANTIBODY IN PATIENTS WITH GRAVES' DISEASE
- VernacularTitle:Graves病患者血清中TSH抗体检测及其免疫学意义
- Author:
Ge CHEN
- Publication Type:Journal Article
- Keywords:
Graves' disease Thyrotropin Autoimmune disease
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
The anti-thyrotropin antibody (TSHab) in 29 normal subjects and 58 patients with Graves' disease (GD) with 125I-TSH as tracer. The TSHab indices were 0.85?0.22 in normal subjects, 1.47?0.35 (P0.05) in GD treated by antithyroid drugs. The result of staphylococus aureus Cowan I precipitation test showed that the antibodies binding to TSH belong to IgG. The existance of TSHab in GD suggested that the reaction of idiotype/anti-Jdiotype was involved in autoimmune mechanism of GD.
