The regulatory effect of Ginsenside on NK cell activity via pituitary-adrenal axis in operative stress
- VernacularTitle:人参皂甙通过垂体—肾上腺轴调整应激期NK细胞的受抑作用
- Author:
Zhonghui LIU
;
Guizhen YANG
- Publication Type:Journal Article
- Keywords:
Ginsenodide;
ACTH;
ACTHR(ACTH receptor);
operative stress
- From:
Chinese Journal of Immunology
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
It was reported that immuno-regulatory mechanism of Ginsenoside on NK cell activity through pituitary-adrenal axis in operation stressed mice. Ginsenoside could modulate NK cell activity in mice against stress. On the other hand the level of plasma ACTH, corticosterone and the splenocyte ACTHR increased in stressed mice, as we know that ACTH, corticosterone could inhibite immunocyte function. However, Ginsenoside decreased the level of ACTH and corticosterone. This result suggests that the regulation effect of Ginsenoside on NK cell activity may be related to the action of pi tui taryadrenal axis under stress conditions.
