A STUDY ON THE FREE SELENICS IN THE SERUM OF RATS AND THEIR KINETICS IN THE MYOCARDIUM
- VernacularTitle:大鼠游离血硒及心肌硒动力学研究
- Author:
Jiong LI
;
Shusheng ZHANG
;
Dequan WANG
- Publication Type:Journal Article
- Keywords:
Keshan disease;
selenium;
radiotracing pharmacokinctics;
isotope
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
By tracing of ~(75)Se-Na_2SeO_3 incubating and irrigating of the isolated myocardial slices of rats, the numeric relationship between the free selenics in the serum and the serum sdenics, the sodium sdenite doses injected were observed; the absorption of the frce selenics and the serum selenics was compared; the setenics metabolic rate and quantities of the myocardial tissue in different duration after injecting of selcnite, the effect of selenics concentration to the participating were calculated, It is suggested that there is a very close relationship between the free selenics and the selenium metabolism in the myocardium; the ratio betwen the values of the free selenics and the serum selenics may become a stable indicator of the selenium metabolism; the free selenics in the serum may be where the important mediates of selenium metabolism are.
