EFFECTS OF DIMETHYL TRILOBINE IODIDE ON THE BLOOD LIPIDS OF RATS AND HEMORRHEOLOGY OF RABBITS
- VernacularTitle:碘化二甲基木防己碱对大鼠血脂及家兔血液流变学的影响
- Author:
Bingxiang YUAN
;
Ying WU
;
Qiusuo MENG
- Publication Type:Journal Article
- Keywords:
dimcthyl trilobine iodide;
lipids;
hemorrheology
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of Dimethyl trilobine Iodide (DTI) on the blood lipids and lipoprotein choieslerol of rats and hemorrheology of rabbits were studied An peritoneal injection of DTI at the dosage of 0.5mg/kg could increase the serum TG of normal rais and reduce the HDL-c and HDL-c/LDL-c of rats fed with normal and fat-rich diets. An intravenous injection of DTI at the dosage of 10?g/kg accelerated formation of thrombus in vitro and at 5?g/kg and 10?g/kg elevated plasma mucosity at high sheafing. It was demonstrated that DTI had probably unfavorable effects on mediation of blood lipids of rats and hemorrheology of rabbits.
