OBSERVATION OF MONONUCLEAR CELLS IN EARLY SKIN LESIONS OF PATIENTS WITH PSORIASIS
- VernacularTitle:银屑病患者初发皮损中单个核细胞的观察
- Author:
Jian REN
;
Yuanqi MA
;
Lisheng SI
- Publication Type:Journal Article
- Keywords:
psoriasis;
early skin lesion;
lymphocyte subsets
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The mononuclear cells in early skin lesions of 10 patients with extensive psoriasis vulgaris in progressive stage were studied by biotin-avidin-peroxidase method using monoclonal antibodies. The results show that increased mononuclear cells in the early skin lesions, expressing HLA-DR antigen mostly, consist of T lymphocytes and macrophases with a preponderance of T lymphocytes, B lymphocytes are absent, activated T lympocytes are usually in close proximity to DR~+ cells including dentritic cells and keratinocytes, indicating that the initial psoriatic lesion correlates closely with imbalance of cellular immunity.
