Study on calmodulin-binding proteins in lympnocytes
- VernacularTitle:淋巴细胞中钙调素结合蛋白的研究
- Author:
Guangyu WU
;
Shenghao ZHAO
- Publication Type:Journal Article
- Keywords:
Calmodulin;
Calmodulin-binding protein;
Lymphocyte;
Overlay
- From:
Chinese Journal of Immunology
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Utilizing the ~(125)I-Calmodulin-overlay technique, we have detected calmodulin-binding proteins (CaMBPs) in crude extracts of lymphocytes. The results indicated that appendix (B cell), mesenteric lymph node (T, B cell) and spleen (T, B cell) from rabbit contained 19, 20 and 16 species of CaMBPs respectively. Ten CaMBPs with molecular weight 80, 78, 70, 63,50, 41, 36, 22, 17 and 13.5 K D were present in all lymphocytes detected. Lymphocytes were rich in two kind of CaMBPs with molecular weight 17 and 13.5 K D which bound calmodulin in partial calcium-dependent manner.