Antibody mediated sperm phagocytosis by rat peritoneal macrophages
- VernacularTitle:在抗体介导下巨噬细胞吞噬精子的作用
- Author:
Huixian WANG
- Publication Type:Journal Article
- Keywords:
Antisperm antibodies;
Macrophage;
Sperm;
Rat;
Phagocytosis
- From:
Chinese Journal of Immunology
1985;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
More recently, a high incidence of antisperm antibodies in men and women with unexplained in fertility has been reported by many authors. However, the antisperm antibodies may play a role in mediating in fertility by interacting with sperm. The effect of antisperm antibodies on the phagocytosis of rat peritoneal macrophages were studied in vitro. The results indicated that opsonization of rat sperm by rabbit anti-rat sperm antibodies increases both the percentage of phagocytosis and phagocytic index apparently. The engulfed sperm when observed by SEM were bended and wrapped up. It seems likely that antisperm antibodies enhanced phagocytosis by macrophages may take part in the antisperm immune responses.
