EXPERIMENTAL STUDY ON ANTIFERTILITY EFFECT OF CYATHULA OFFICINALIS KUAN
- VernacularTitle:川牛膝提取物抗生育作用的实验研究
- Author:
Qianwu LI
- Publication Type:Journal Article
- Keywords:
Cyathula officinalis kuan;
antifertility, antinidation
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
The antifertility and antinidation effects of three extracts (benzol, ethyl acetate and alcohol) of Cyathula Oficinalis Kuan on mice were observed. The results indicate that the benzol extract had significant antifertility action. Its effective rate of antifertility was 100%, when 250 mg/kg was given orally. As compared with control, when 250 mg/kg ethyl acetate extract was given, the rate of antifertility was 63.7%. If 500 mg/kg ethyl acetate extract was given the effective rate of antifertility increased over 90%. However, when 250～500 mg/kg alcohol extract was given, the rate of antifertility was only 40～54%. The study of antinidation showed that the benzol extract (500 mg/kg )could effectively prevent implatation. The rate of antinidation was 100%, and yet the ethyl acetate and alcohol extracts were 66.7% and 40% repectively. The results suggest that the three extracts of Cyathula Officinalis Kuan all had antifertility effect, but the action of benzol extract was more effective than other two extracts.
