Dynamic changes of immunoreactive ?-endorphine levels in pituitary and hypothalamus during immune response
- VernacularTitle:免疫应答中垂体及下丘脑?—内啡肽样免疫反应性物质含量的动态变化
- Author:
Jianping WANG
- Publication Type:Journal Article
- Keywords:
wordect plaque forming cell;
Pituitary;
Hy(?)othalamus;
Immunoreactive ?-endorphine;
Neuroimmunomodulation
- From:
Chinese Journal of Immunology
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The present study attempts to investigate the influence of the immune response upon the immunoreactive ?-endorphine (ir-?-EP) levels in anterior lobe (AL) and neurointermediate lobe (NIL) of pituitary and hypothalamus after immunizaion of male adult Wistar rats with sheep erythrocytes by a single intraperitoneal injection. The results showed that the decrease of ir-?-EP concentration in AL tended to be concomitant with the direct plaqueforming cells (direct PFC) level increased. In the 3rd day after immunization, when a few PFC began to appear, the concentration of ir-?-EP in AL decreased significantly (P