INTRACEREBRAL PANCREAS ISLET TRANSPLANTATION FOR THE TREATMENT OF TYPE I DIABETES MELLITUS
- VernacularTitle:脑内胰岛移植治疗Ⅰ型糖尿病
- Author:
Yanhu DONG
- Publication Type:Journal Article
- Keywords:
Intracerebral pancreas islet transplantation Type I diabetes mellitus Immunologically privilegd site
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
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Abstract:
Ten cases of type I diabetes mellitus were treated with intracerebral pancreas islet transplantation. In 7 cases insulin has been totally stopped for 2 to 13 months, in other 2 cases the dosages of insulin had a decrease of 37% and 64% than that before transplantation respectively, and good control was achieved in those 9 patients. Only one case had not any improvement. The results showed that it is an effective therapy for type I diabetes mellitus and indicated that the pancreas islet was survived in patient's cerebrum and secreted insulin. No evidence of immunological rejection was found. Long-term follow-up is necessary to find how long the allogenic graft can survive.
