THE CHANGES OF ATRIAL NATRIURETIC FACTOR IN DIABETES MELLITUS AND ITS CLINICAL SIGNIFICANCE
- VernacularTitle:血浆心钠素在糖尿病的变化及临床意义
- Author:
Weibin ZHAO
- Publication Type:Journal Article
- Keywords:
Atrial natriuretic factor Diabetes mellitus Insulin
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
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Abstract:
The mean plasma ANF level in 48 patients with diabetes mellitus was higher than that in normal subjects (875.2 ? 50.0vs542.5 ? 23.8ng/L). And ANF levels were positively correlated with serum insulin and the dimension ofleft atria. There was some relationship between ANF and cardiac autonomic function score, but it's not statistically significant. No significant correlation was observed between plasma ANF and the duration of diabetes, urine sodium, blood glucose or HbA1C levels. The levels of plasma ANF in 9 patients with cardiac complication and 6 patients with diabetic nephro-pathy were both higher than that in patients without any obvious complication. The decrease of plasma ANF in OGTT was due to a fall of extracellular volume, and had little relation with the changes of serum insulin.
