EFFECT OF INSULIN ON PRODUCTION AND ACTION OF IL-1
- VernacularTitle:胰岛素对白细胞介素1产生及作用的影响
- Author:
Yi LUO
- Publication Type:Journal Article
- Keywords:
Insulin;
IL-1
- From:
Chinese Journal of Immunology
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
In our experiment it was found thatinsulin was able to significantlyenhance the response of the thymo-cytes treated with nylon wool toConA in the presence of exogenousIL-1.It had been demonstrated thatinsulin was able to augment the pro-duction of IL-1 by macrophagesstimulated by LPS.These resultssuggest that the regulation of insulinon T cell activiation be associatedwith macrophages or IL-1 andinsulin play a regulating rolein other reactions mediated withIL-1.In addition,it was alsodemonstrated that the action of activeinsulin could be weakened if inac-tive insulin be not removed.
