DYNAMIC CHANGES AND ITS SEX DIFFERENCES OF PLASMA TESTOSTERONE LEVEL FOLLOWING MYOCARCIAL INFARCTION IN RATS
- VernacularTitle:心肌梗塞大鼠血浆睾酮水平的动态变化及其性别差异
- Author:
Liquan LEI
- Publication Type:Journal Article
- Keywords:
myocardial infarction;
testosterone;
rat;
sex difference
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Serial observation were made on the variations of plasma testosterone (T) level from 6 hours to 21 days after myocardial infarction (MI) in male and female rats; In the male MI group, plasma T level was reduced by 76% 6 hours after ligation of the left coronary artery. 24 hours after MI, there was a small increase in the T evel, but it was all along significantly lower than preoperative level from 6 hours up to 21 days postoperatively. In the female rats, however, plasma T level was increased by 50% 24 hours postoperatively and returned to the preoperative level 9 days after MI, It is suggested that sex diffe rences in mortality, recovery and compen sation of left ventricular function after MI in the rats might be related to the changes of the plasma T level.
