THE INVESTIGATION OF THE PRIMARY RELATIVES OF 200 CASES WITH SIMPLE OBESITY
- VernacularTitle:200例单纯性肥胖患者的一级亲属调查
- Author:
Aihua XU
- Publication Type:Journal Article
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
In order to study the pathogenesis of simple obesity in relation to genetic and environmental factors,I,202 primary re-latives of 200 cases of simple obesity and 939 primary relatives of 200 normal controls were investigated. The results were as follows: The incidence of obesity is higher in the parents and siblings of obese subjects than that in the normals. The hereditary degree is 83.1% in these patients with simple obesity. Asignificant difference of the incidence of obesity was found between the normal controls (11.7%) and the primary relatives of obese cases (34.4%). The latter is close to the square root of the former and is much less than that of the monofactorial inheritance. Therefore, genetic factors and multifactorial inheritance appear to play a role in the pathogenesis of obesity.
