FIBRONECTIN IN HUMAN BREAST TUMORS
- VernacularTitle:乳腺瘤组织内纤维连结蛋白分布的变化
- Author:
Ping LIANG
- Publication Type:Journal Article
- Keywords:
Fibronectin;
Breast Tumor;
Basement Membrane.
- From:
Chinese Journal of Immunology
1985;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Fibronectin in normal human breast tissue and in breast tumors were stu-died by immuno-gold silver staining method.In normal mammary tissue,fibronectin was present in basement membrane and stroma but absent in epi-thelial cells.Changed distribution pattern was observed in benign tumorsand malignant tumors,there was an appearance of fibronectin in epithelialcells of acini and ductules and decreased in stroma.The differences wasthat fibronectin decreased in basement membrane in benign tumors and dis-appeared in that of malignant tumors which reflect to some extent the inva-sive nature of tumors.