HYPERLACTACIDEMIA DUE TO PHENFORMIN IN NIDDM
- VernacularTitle:降糖灵治疗40例非胰岛素依赖型糖尿病引致高乳酸血症临床研究
- Author:
Wenzhong FENG
- Publication Type:Journal Article
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
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Abstract:
Having been given Phenformin (DBI) for up to 6 months, 40 cases of NIDDM with normal hepatic and renal functions showed various degrees of hyperlactacidemia. The mean value of hyperlactacidemia increased with ages, but had no relation to the course of disease. Since DBI is liable to cause hyperlactacidemic coma, it is suggested that DBI, if indicated,should be used with great prudence, especially for those senile diabetics with impaired hepatic and renal functions.
