CLINICAL SIGNIFICANCE OF PLASMA ACTH AND SERUM CORTISOL RADIOINMUNOASSAYS
- VernacularTitle:放射免疫测定血浆ACTH和血清皮质醇的临床应用
- Author:
Yinzhang WANG
- Publication Type:Journal Article
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
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Abstract:
The clinical significance of plasma ACTH and serum cortisol radioimmunoassays was evaluated. It was found that Addison's disease was characterised by high plasma ACTH and low serum cortisol. Adrenal tumors could be distinguished from Cushing's disease by low plasma ACTH level. The levels of both ACTH and cortisol were elevated in most patients with Cushing's diserse, and yet lowered in hypopituitarism; they had some overlap with normal values in either case. The low-dose dexamethasone suppression test was helpful to differential diagnosis between Cushing's disease and simple obesity. The aminoglutethimide test could be used to distinguish hypopituitarism from normal.In addition, the levels of ACTH and cortisol were measured in patients with obesity, hyperthyroidism and diabetes mellitus.
