EFFECTS OF DL-TETRAHYDROPALMATINE ON ACTION POTENTIALS AND CONTRACTILITIES OF GIUNEA PIG PAPILLARY MUSCLES AND ITS LOCAL ANESTHETIC ACTION
- VernacularTitle:DL—四氢巴马汀对豚鼠心乳头肌动作电位和收缩力的影响及局部麻醉作用
- Author:
Dongke ZHAO
- Publication Type:Journal Article
- Keywords:
tetrahydropalmatine;
papillary muscles;
action potentials;
anesthesia;
local
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of DL-tetrahydropalmatine (THP)on action potentials and contractilies of isolated giunea pig papillary muscle cells were observed with the microelecorode technique. THP(10~(-5)-3x10~(-4)M)could produce a dose-dependent negative inotropic effect. THP(0.1 mM)could shorten APD_(20) and APD_(50) evidently (p
