EFEECT OF ALPHA-INTERFERON COMBINED WITH SILYBUM MARINANUM COMPOUND IN TREATMENT OF CHRONIC HEPATITIS B
- VernacularTitle:人白细胞干扰素联合复方水飞蓟蜜丸治疗乙型慢性肝炎的疗效观察
- Author:
Yifang LI
- Publication Type:Journal Article
- Keywords:
interferons;
silybum mrinanum compound;
hepatitis B
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
This paper reports the results of 15 cases of chronic hepatitis B treated with alpha-inter -feron (?-IFN) combined with silybum marinanum compound at a small dose (?-IFN 5000 units/day)in a long treatment course(3-6 months). The cure rate was 66.6% in the treatment group and 33.3% in the placebo group. The amount of ?-IFN in the serum of the patients was determined before and after treatment, but no ?-IFN in the serum was detected before treatment, ?-IFN elevated to 5-40 units/ml after treatment for 3-7 months. However, it would drop when the treatment was stopped. The therapeutic effect was remarkable when the amount of ?-IFN in the serum was increased. The results indicate that the anti-viral drug(IFN)combined with silyoum marinanum compound may be used to cure chronic hepatitis B.
