EPIDURAL BLCOK BY BUPIVACAINE IN EPIGASTRIC SURGERY——CLINICAL PHARMACOLOGICAL COMPARISON OF BUPIVACAINE MADE IN CHINA AND ABROAD
- VernacularTitle:布比卡因用于上腹部手术硬膜外阻滞(国产和进口药临床药理比较)
- Author:
Pingan YE
- Publication Type:Journal Article
- Keywords:
epidural block;
bupivacaine;
surgery
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Epigastric surgery (76 cases )was performed under epidural block by 0.5% bupivacaine, including 43 patients receiving bupivacainc made in China and 33 cases receiving it made abroad. Bupivacainc made in China was compared with that imported. The onset and duration of action and of Post-oprative analgesia were not significantly different in both groups. Effects of adrenaline on the duration of bupivacaine were not significiant. Both gave good analgesia and muscle relaxation, and toxication was not detected. However, a fall in the blood pressure during bupivacainc analgesia was shown more often than that during lidocaine analggesia. This suggests that sympathetic preganglionic fibers are sensitive to bupivacaine.