DETERMINATION OF BLOOD GROUP SUBSTANCES OF CHORIONIC VILLI AS DIAGNOSTIC METHOD FOR MOTHER-FETUS BLOOD GROUP INCOMPATIBILITY IN EARLY PREGNANCY
- VernacularTitle:一种新的孕早期诊断母儿血型不合方法—绒毛血型物质测定
- Author:
Hong MA
- Publication Type:Journal Article
- Keywords:
blood group substances;
blood group incompatibility;
chorionic villi;
pregnancy trimester, first
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
Mother-Fetus ABO blood group incompatibility is one of the most common causes of hemolytic disease of newborns in China. To identify the blood group of the fetus in case of suspected mother-fetus blood group incompatibility in the first trimester of pregnancy, the author determined blood group substance (BGS) in 40 chorionic villi samples taken by the absorption-elution procedure during 6 to 12 weeks of gestation, with a simultaneous parental blood group determination as control. The BGS detected in those specimens were all in accordance with those of the blood groups of their coriesponding parents. Among the 40 samples of chorionic villi, 20 were redetermined, and the results were the same. This demonstrates the feasibility of the procedure to identify the fetal blood groups by the determination of BGS in the chorionic villi by transcervical aspiration. The study presents, apparently, a new and simple diagnostic method for detecting mother-fetus blood incompatibility in early pregnancy, thas giviing a prospectively preventive study on those types of blood group incompatibility.
