THE ESTABLISHMENT AND EVALUATION OF AN ISOLATED WORKING HEART PERFUSION SYSTEM OF RATS
- VernacularTitle:大鼠离体作功心脏灌流模型的建立及其评价
- Author:
Junhong WANG
- Publication Type:Journal Article
- Keywords:
perfusion;
cardiac function;
rats
- From:Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
In order to take advantage of the model of rat in cardiovascular research, get rid of the influences of the nerve and humoral factors to cardiac function, fix the cardiac load state, and obtain such valuable indices as ejection fraction, left ventricular volume, etc., an isolated working heart perfusion system was set up to observe the changes of the cardiac systolic and diastolic function, ventricular compliance and pumping function. The results of a series of experiments indicated that the stability and responsibility of this perfusion model are satisfactory. The results of coronary ligation and reperfusion were correspondent to those of other authers. This perfusion system can be used in the studies of physiolgoy, biochemistry, pharmacology and pathophysiology.
