Systematic Review on Reduced Glutathione in the Treatment of Drug-induced Liver Disease
- VernacularTitle:还原型谷胱甘肽治疗药物性肝病的系统评价
- Author:
Mei HE
;
Mei ZHAN
;
Ruming LIU
;
Yao TANG
- Publication Type:Journal Article
- Keywords:
Reduced glutathione;
Drug-induced liver disease;
Toxipathic liver disease;
Systematic review
- From:
China Pharmacy
2007;0(32):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To evaluate the efficacy of reduced glutathione in the treatment of drug-induced liver disease. METHODS: Literatures were retrieved from PubMed, Medline, EMBASE, Cochrane Library, CBM, VIP, CNKI databases by computer and from relevant Chinese medical journals by hand. Trial selection, quality evaluation and information extraction were performed according to including and excluding criteria. Meta-analysis was conducted using RevMan 5.0 software. RESULTS: The meta-analysis of 13 included RCTs showed that total effective rate, ALT and total bilirubin in trial group were significantly different from control group(P
