Analysis of Uncertainty of Measurement in the Determination of Roxithromycin Dispersible Tablets by HPLC
- VernacularTitle:HPLC法测定罗红霉素分散片含量的测量不确定度分析
- Author:
Dengping ZUO
;
Zhengyu WANG
- Publication Type:Journal Article
- Keywords:
Roxithromycin dispersible tablets;
Uncertainty;
HPLC;
Content determination
- From:
China Pharmacy
2007;0(32):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To find out the critical influential factors of measurement in the determination of Roxithromycin dispersible tablets. METHODS: Mathematic model of HPLC was established to analyze the effects of many uncertain factors on measurement results. Combined standard uncertainty and expanded standard uncertainty were calculated. RESULTS: The expanded uncertainty was 1.6% and the results of determination could be expressed as (96.8?1.6)%. CONCLUSION: The established analytical method is applicable to the uncertainty analysis in the content determination of Roxithromycin dispersible tablets by HPLC.
