Stability Predictions of 5% Glutaraldehyde Solution Using Classic Constant Temperature Accelerated Test Method
- VernacularTitle:经典恒温加速法预测0.5%戊二醛溶液的稳定性
- Author:
Yujun CHEN
;
Shaowen ZHANG
;
Hongzhen GUAN
;
Yu FENG
;
Xin LIU
- Publication Type:Journal Article
- Keywords:
Glutaraldehyde;
Classic constant temperature accelerated test method;
Sample observation method;
Stability
- From:
China Pharmacy
2007;0(32):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To investigate the stability of 0.5% glutaraldehyde solution. METHODS: Classic constant temperature accelerated test method and sample observation method were applied with the content of glutaraldehyde as index. The content of glutaraldehyde was determined by titration which was determined by titration. RESULTS: The content change of 0.5% glutaraldehyde solution was in line with the first order kinetics, and the results of both methods were similar. The validity duration of 0.5% glutaraldehyde solution was 85.7 days at room temperature (25 ℃). CONCLUSION: 0.5% glutaraldehyde solution should be used up as soon as possible and the perfect time is less than 2 week.
