Optimization of the Extraction Technology of Huanggan Decoction by Orthogonal Experiment
- VernacularTitle:正交试验优选黄肝煎液的提取工艺
- Author:
Jing CHEN
;
Yanping HE
- Publication Type:Journal Article
- Keywords:
Huanggan decoction;
Chlorogenic acid;
Extraction technology;
Orthogonal experiment
- From:
China Pharmacy
2007;0(31):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To optimize the extraction technology of Huanggan decoction. METHODS: The extraction technology of Huanggan decoction was optimized by L9(33) orthogonal design with the concentration of alcohol, the amount of solvent and the extraction time as factors taking the contents of chlorogenic acid as indexes. RESULTS: The optimal extraction process was as follows: adding six and five-fold of 70% alcohol, extracting for 60 min and 45 min. CONCLUSION: The extraction technology has been proved to be reasonable, simple and feasible, and it provides theory evidence for production.
