Study on Formulation Process of Rutongning Granule
- VernacularTitle:乳痛宁颗粒成型工艺研究
- Author:
Maohui ZHANG
;
Jun ZHAO
;
Xianlin LI
;
Jianhua WANG
- Publication Type:Journal Article
- Keywords:
Rutongning granule;
Formulation process;
Critical relative humidity
- From:
China Pharmacy
2007;0(31):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study optimal formulation process of Rutongning granule. METHODS: The ratio of main components to excipients was optimized with hygroscopicity,granulation and dissolubility index. RESULTS: The optimal ratio of extract powder to saccharose was 1 ∶ 1.5. The made granules were characterized with low hygroscopicity, high granulation,high dissolubility and low cost. And its critical relative humidity was 65%. CONCLUSION: The study provides theory evidence for formulation process of Rutongning granule and the control of production environment.
