Effect of IL-6 on the proliferation of QBC939 and the expression of Bcl-2mRNA
- VernacularTitle:外源性IL-6对胆管癌细胞的抗凋亡作用及其对Bcl-2mRNA的调控
- Author:
Wei LIU
;
Huihuan TANG
- Publication Type:Journal Article
- Keywords:
Bile Duct Neoplasms;
Interleukin-6;
Bcl-2;
Apoptosis
- From:
Chinese Journal of General Surgery
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the effect of exogenous IL-6 on the proliferation of cholangiocarcinoma cell line QBC939.Methods MTT was used to observe the proliferation of cell line QBC939 treated with exogenous IL-6.Following the annexin V/FITC and PI staining,FCM was used to detect the apoptosis of QBC939 treated with exogenous IL-6.Results The proliferation of cell line QBC939 was increased after treatment with IL-6 and was positively related with the concentration of IL-6(P
