Analysis of 347 ADR Cases Induced by Antibiotics in Our Hospital
- VernacularTitle:我院347例抗菌药物致不良反应分析
- Author:
Tingchao LIU
;
Zhigang LI
- Publication Type:Journal Article
- Keywords:
Antibiotics;
ADR;
Report;
Analysis
- From:
China Pharmacy
2007;0(30):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the cause and characteristics of ADR cases induced by antibiotics in our hospital.METHODS:347 ADR cases induced by antibiotics collected from our hospital from 2005 to 2009 were analyzed statistically.RESULTS:Of total 347 ADR cases,9 kinds of antibiotics were involved.Most of ADR cases were induced by quinolones and cephalosporins,accounting for 36.60%(127 cases) and 22.77%(79 cases).Among them,levofloxacin and ceftriaxone took up the biggest proportion,accounting for 14.70% and 12.39%.Main clinical manifestations were lesion of skin and its appendants(158 cases,42.36%).175 ADR cases were caused by unreasonable use of drugs(50.43%),in which the primary cause was false selection of dosage,followed by medication for no infectious characteristics,inappropriate drug selection,unseasonable drug combination and false selection of solvent.Of 175 ADR cases caused by unreasonable use of drugs,cephalosporins antibiotics took the largest portion(46.29%).CONCLUSION:Antibiotics-induced ADR are related with many kinds of factors.It is very important to pay more attention to rational use antibiotics in case unreasonable use of antibiotics results in serious ADR.Furthermore,ADRs will be reduced greatly through reasonable and normal use of antibiotics.
