Influence of Shanghai Guiding Principles of Clinical Use of Antibiotics Implementing Rules(Trial) on Prophylactic Use of Drugs in Patients Underwent General Surgery Operation
- VernacularTitle:施行《上海市〈抗菌药物临床应用指导原则〉实施细则(试行)》对我院普外科手术患者预防性用药的影响
- Author:
Yan ZHU
;
Qiong LIU
- Publication Type:Journal Article
- Keywords:
Perioperative period;
Antibiotics;
Prophylactic use of drugs;
Contrast analysis
- From:
China Pharmacy
2007;0(30):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To discuss the influence of Shanghai Guiding Principles of Clinical Use of Antibiotics Implementing Rules(Trial)(named Implementing Rules for short) on prophylactic use of drugs in patients underwent general surgery operation.METHODS:In retrospective study,inpatients of general surgery department in our hospital from Sep.2006 to Feb.2008 were divided into 3 groups(Group 1:6 months before Implementing Rules issued;Group 2:0～6 months after Implementing Rules issued;Group 3:7～12 months after Implementing Rules issued).The utilization of antibiotics was analyzed as well as its rationality.RESULTS:A total of 1 308 cases were enrolled.The utilization frequency of antibiotics was 3 463.Less than half of cases met the indication of antibiotics while the rate of drug sensitivity test was 1.2%.The treatment courses of 3 groups were(3.4?4.3) d,(3.3?2.9) d and(3.1?3.0) d.The proportions of rational drug use were 36.5%,35.1% and 40.7%.But the selection of antibiotics,drug combination and ADR report were not significantly improved.CONCLUSION:The issue of Implementing Rules has promoted the rational use of antibiotics in general surgery department.Further training and monitoring are needed.
