Preparation and Quality Control of Nicotinamide Gel
- VernacularTitle:烟酰胺凝胶的制备及质量控制
- Author:
Meilan LUO
;
Minqiang HE
- Publication Type:Journal Article
- Keywords:
Nicotinamide gel;
Preparation;
Quality control;
UV-visible spectrophotometry
- From:
China Pharmacy
2007;0(29):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To prepare Nicotinamide gel and to establish its quality control method.METHODS: Nicotinamide gel was prepared using nicotinamide as main ingredient,and the content of nicotinamide was determined by UV-visible spectrophotometry.RESULTS: Preparation was colorless gel,and its identification and test were all in conformity with the related regulation stated in Chinese Pharmacopoeia(2010 edition).The linear range of nicotinamide was 6.24～16.64 ?g?mL-1(r=0.999 5) with an average recovery rate of 102.0%(RSD=0.33%,n=5).CONCLUSION: The preparation procedure is simple and feasible,and the quality of the preparation is stable and controllable.
