Significance of Fas, FasL and FADD expression in squamous cell carcinoma of larynx
- VernacularTitle:喉癌中Fas、FasL和Fas相关死亡结构域蛋白的表达及其意义
- Author:
Haili SUN
;
Hua GUO
;
Yuhe LIU
;
Ting LI
;
Shuifang XIAO
- Publication Type:Journal Article
- Keywords:
Laryngeal Neoplasms;
Carcinoma, Squamous;
Apoptosis Regulatory Proteins;
Apoptosis
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the expression and significance of Fas, FasL and FADD in laryngeal carcinoma. METHODS Immunohistochemical method was used to examine the expression of Fas, FasL and FADD in laryngeal carcinoma specimen and adjacent normal tissues. RESULTS The positive rates of Fas and FADD in laryngeal carcinoma tissue were significantly lower than that in adjacent normal tissue, while FasL in laryngeal carcinoma tissue was higher than that in adjacent normal tissue(P
