Experimental Study on Endothelial NO-dependent Vasodilation Effect of the Extracts of Herba Siegesbeckiae
- VernacularTitle:豨莶草提取物对血管内皮NO依赖作用的研究
- Author:
Yalan YANG
;
Jianlin LU
- Publication Type:Journal Article
- Keywords:
Extracts of Herba Siegesbeckiae;
Endothelial NO-dependent vasodilation effect;
Anti-hypertensive
- From:
China Pharmacy
2007;0(27):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study endothelial NO-dependent vasodilation effect of the extracts of Herba Siegesbeckiae. METHODS:SD rat thoracic aorta rings were used to observe contraction of blood vessel, and the effects of the extracts of Herba Siegesbeckiae on the contraction induced by phenylphrine (PE). RESULTS:The extract of Herba Siegesbeckiae could inhibit the contraction of blood vessel induced by PE. After pretreatment of blood vessel by L-NNA, vasodilation effect of the extracts of Herba Siegesbeckiae was significantly attenuated at low concentration condition(P
