Basic research and clinical significance of chromogranin A
- VernacularTitle:嗜铬粒蛋白A的基础研究与临床意义
- Author:
Yeqing XIE
;
Ruizhen CHEN
- Publication Type:Journal Article
- Keywords:
Chromogranin A;
Disease;
Basic research
- From:
Chinese Journal of Pathophysiology
2000;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Chromogranin A (CGA) has been considered as the most useful indicator of neuroendocrine activity.It is the precursor of many biologically active peptides produced by proteolytic cleavage,which play their roles in a large variety of patterns in different tissue.Clinically,CGA is of diagnostic and evaluation value in several diseases.The protein structure,biological and physiological functions as well as the clinical significance of CGA are reviewed in this article.