Study on Compatible Stability of Cefepime Dihydrochloride Mixed with Total Parenteral Nutrient
- VernacularTitle:盐酸头孢吡肟与全静脉营养液的配伍稳定性考察
- Author:
Xiaodong WANG
- Publication Type:Journal Article
- Keywords:
Hydrochloride cefepime;
Total parenteral nutrient;
Compatibility;
Stability
- From:
China Pharmacy
2007;0(26):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the compatible stability of cefepime dihydrochloride mixed with total parenteral nutrient(TPN). METHODS:Cefepime dihydrochloride mixed with TPN at room temperature for 24 h. The appearances of the mixture were observed at 0,2,4,6,8,10,24 h and the change of pH value was evaluated. The contents of cefepime dihydrochloride were determined by HPLC. RESULTS:No change was observed in the contents of cefepime dihydrochloride in total parenteral nutrient within 24 h. There was no significant change in the appearance,color and pH value of nutrient. CONCLUSION:At room temperature cefepime dihydrochloride in TPN is stable within 24 h.
