Systematic Review on Omeprazole and Ranitidine in the Treatment of Peptic Ulcer
- VernacularTitle:奥美拉唑和雷尼替丁治疗消化性溃疡的系统评价
- Author:
Hongyan SHI
- Publication Type:Journal Article
- Keywords:
Omeprazole;
Ranitidine;
Systematic review;
Evidence-based medicine
- From:
China Pharmacy
2005;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate clinical efficacy and ADR of omeprazole and ranitidine in the treatment of peptic ulcer.METHODS:Literatures were retrieved from China scientific journal database and Wanfang database.Meta-analysis was conducted using Revan 5.0 software.Fixed effect model was used to combined information and non-heterogeneity.The cause of heterogeneity was also analyzed.Sensitivity analysis and subgroup analysis were used to dispose the heterogeneity.Random effect model was used for analysis if the heterogeneity cannot be eliminated.RESULTS:Total effective rate of omeprazole for peptic ulcer was significantly different from ranitidine [P
