Study on Antiemetic Effect of Capsicum frutescens
- VernacularTitle:辣椒的止呕作用研究
- Author:
Zhihong YANG
;
Wang YUE
;
Zhantao LIU
;
Fang ZHANG
;
Yaoxia WANG
;
Dexue ZHAO
- Publication Type:Journal Article
- Keywords:
Capsicum fruescens;
Antiemetic effect;
5-HT;
SP;
Minks
- From:
China Pharmacy
2005;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the antiemetic effects of Capsicum frutescens and its mechanism.METHODS: Novel vomiting model of minks were established.Inhibition effect of C.fruescens(capsicin as main component) on vomiting behavior induced by cisplatin and apomorphine were observed.The mechanism was investigated through the immunohistochemistry test and the specific 5-HT3-receptor agonist 1-phenylbiguanide hydrochloride(PBG).RESULTS: C.frutescens inhibited vomiting behavior of minks induced by cisplatin and apomorphine(P
