Study on Shattering Extraction with Solvent for Jingzhi Guanxin Granules
- VernacularTitle:湿法粉碎提取精制冠心颗粒工艺的研究
- Author:
Qiaoru LI
;
Ping GUO
;
Wenhui SONG
;
Bo ZHAO
- Publication Type:Journal Article
- Keywords:
Shattering extraction with solvent;
Extraction technology;
Jingzhi guanxin granules
- From:
China Pharmacy
2005;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To optimize the extraction technology of Jingzhi guanxin granules.METHODS: The extraction technology of Jingzhi guanxin granules were optimized using shattering extraction with solvent,refluxing extraction and primary extraction with the content of tanshinone ⅡA,salvianolic acid B,paeoniflorin,ferulate and hydroxysafflor yellow A and extraction rate as index.RESULTS: The optimal extraction process was as follows: Jingzhi guanxin powder,6 fold 95% alcohol,extracting for 10 min in the first time,6 fold 60% alcohol,extracting for 10 min in the second,6 fold 20% alcohol,extracting for 10 min in the third.CONCLUSION: Using shattering extraction with solvent for Jingzhi guanxin granules,extraction rate of each constituent are higher than that of primary extraction.This extraction process is simple in operation and save time.
